Journal
CURRENT OPINION IN LIPIDOLOGY
Volume 18, Issue 5, Pages 566-573Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOL.0b013e3282ef7c1e
Keywords
atherosclerosis; differentiation; foam cells; platelets; progenitor cells
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An expanding body of evidence continues to build on the role of platelets as initial actors in the development of atherosclerotic lesions. Platelets bind to leukocytes, endothelial cells, and circulating progenitor cells and initiate monocyte transformation into macrophages. Therefore platelets regulate the initiation, development and total extent of atherosclerotic lesions.
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