4.7 Article

Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 51, Issue 10, Pages 3768-3770

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00239-07

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Trioxaquines, potential antimalarial agents, and heme-artemisinin adducts, resulting from the alkylation of heme by artemisinin, were evaluated as inhibitors of P-hematin formation in 10 M acetate medium at pH 5.

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