Journal
EXPERT OPINION ON PHARMACOTHERAPY
Volume 8, Issue 14, Pages 2293-2305Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/14656566.8.14.2293
Keywords
ovarian cancer; platinum; recurrence; secondary debulking
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Epithelial ovarian cancer will strike between 1-2% of women in developedcountries and, unfortunately, it largely remains a lethal disease due to late-stage at diagnosis and the eventual development of chemotherapy resistance. Ovarian cancer is initially treated with surgical resection and chemotherapy (primarily platinum/taxane combinations) and remission can be attained for the majority of patients. Despite this, most women will recur and require multiple further therapies. The purpose of this paper is to review the existing treatment options, including surgery, traditional chemotherapy as well as upcoming novel and targeted therapies that may one day improve outcomes in this disease.
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