Journal
JOURNAL OF ANTIBIOTICS
Volume 60, Issue 10, Pages 645-648Publisher
SPRINGERNATURE
DOI: 10.1038/ja.2007.83
Keywords
JBIR-03; indole-diterpene; Dichotomomyces cejpii; MRSA; Valsa ceratosperma
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A new indole-diterpene, JBIR-03 (1), was isolated from the fungus Dichotomomyces cejpii var. cejpii NBRC 103559 and its structure was determined based on the spectroscopic data. 1 exhibited anti-MRSA (methicillin-resistant Staphylococcus aureus) activity and antifungal activity against apple Valsa canker-causing fungus, Valsa ceratosperma, while it exhibited no toxicity towards human cancer cells.
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