4.7 Article

Rapid field immunoassay for detecting antibody to Sin Nombre virus in deer mice

Journal

EMERGING INFECTIOUS DISEASES
Volume 13, Issue 10, Pages 1604-1607

Publisher

CENTER DISEASE CONTROL
DOI: 10.3201/eid1310.070356

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Funding

  1. NIAID NIH HHS [N01AI25489, AI054461, R15 AI054461] Funding Source: Medline
  2. PHS HHS [US3/CCU 813420-09] Funding Source: Medline

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We developed a 1-hour field enzyme immunoassay (EIA) for detecting antibody to Sin Nombre virus in deer mice (Peromyscus maniculatus). The assay specificity and sensitivity were comparable to those of a standard EIA. This test will permit identification of rodents with antibody to this and perhaps other hantaviruses.

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