Journal
SCIENCE IN CHINA SERIES C-LIFE SCIENCES
Volume 50, Issue 5, Pages 611-618Publisher
SCIENCE PRESS
DOI: 10.1007/s11427-007-0086-1
Keywords
Hong Kong seaweed; hydroclathrus clathratus; antiviral polysaccharide; polysaccharide characterization
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Two relatively pure polysaccharides H3-a1 and H3-b1 had been isolated from the brown seaweed Hy-. droclathrus clathratus. They were characterized by HPLC, ultraviolet scanning, gas chromatography, infrared spectroscopy and elemental analysis, and shown to be two different sulfated polysaccharides with different monosaccharide content, but both with high relative molecular mass. They contained some proteins and uronic acid respectively. The sulfate content and bioactivity of these polysaccharides varied during purification. The fractions derived from the hot water extract also exhibited low anticoagulant effect. This is the first time that the antiherpetic and anticoagulant activities were evaluated for the polysaccharides from the Hong Kong brown seaweed Hydroclathrus clathratus.
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