Journal
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
Volume 54, Issue 5, Pages 1679-1686Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TNS.2007.901227
Keywords
PET; scatter correction; single scatter simulation (SSS); time-of-flight (TOF)
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We extend the single scatter simulation (SSS) algorithm for scatter correction of three dimensional positron emission tomography to include the case in which the scattered annihilation radiation is discriminated according to its differential time-of-flight (TOF). Good agreement between computed and measured TOF dependent scatter is observed in phantom and human data. Significant differences between TOF dependent and non-TOF dependent scatter are found. Because TOF scoring removes the degeneracy in ray sum calculations, TOF SSS takes about seven times longer than non-TOF SSS to compute the scatter sinogram itself. However, when the overhead due to image computation and iteration is factored in, the clinical performance is only a factor of slower.
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