4.7 Article

Synthesis and resolution of planar-chiral derivatives of 4-(Dimethylamino)pyridine

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 349, Issue 14-15, Pages 2345-2352

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200700219

Keywords

asymmetric catalysis; asymmetric synthesis; heterocycles; homogeneous catalysis

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A safer and more efficient method for the synthesis of planar-chiral 4-(dimethylamino)pyridine (DMAP) derivatives has been developed. Racemic mixtures of the complexes can be resolved via classical resolution with commercially available tartaric acids.

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