Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 39, Pages 11900-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja073936h
Keywords
-
Categories
Funding
- NCI NIH HHS [P50 CA114747, R01 CA082214, U54 CA119367, 5R01 CA082214] Funding Source: Medline
Ask authors/readers for more resources
We report here syntheses of bisdeoxycoelenterazine derivatives that show significantly improved kinetics of the bioluminescent reaction. All derivatives contain a protecting group at the carbonyl group of the imidazopyrazinone moiety that ensures slower light signal decay. The longer lasting light signal offers the possibility of real-time imaging of protein-protein interactions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available