Journal
CELL
Volume 131, Issue 1, Pages 29-32Publisher
CELL PRESS
DOI: 10.1016/j.cell.2007.09.026
Keywords
-
Categories
Ask authors/readers for more resources
Methylation of lysine 27 on histone H3 ( H3K27me) by the Polycomb complex (PRC2) proteins is associated with gene silencing in many developmental processes. A cluster of recent papers ( Agger et al., 2007; De Santa et al., 2007; Lan et al., 2007; Lee et al., 2007) identify the JmjC-domain proteins UTX and JMJD3 as H3K27-specific demethylases that remove this methyl mark, enabling the activation of genes involved in animal body patterning and the inflammatory response.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available