4.8 Article

Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from baylis-hillman adducts of isatin and heteroaldehydes with azomethine ylides via [3+2]-cycloaddition

Journal

ORGANIC LETTERS
Volume 9, Issue 21, Pages 4095-4098

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol701533d

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A novel regioselective synthesis of a number of functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts; of isatin and heteroaldehydes via [3+2] cycloaddition of azomethine ylides in excellent yields has been reported.

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