Journal
ANAEROBE
Volume 24, Issue -, Pages 90-93Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.anaerobe.2013.09.010
Keywords
Oral bacteria; Systemic disease; Focal sepsis; Focal infection; Periodontal medicine
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It is well known that bacteria are the primary cause of infectious diseases, however, evidence is emerging that these organisms are also indirectly responsible for several diseases including cancer and rheumatoid arthritis. The oral cavity is home to several million bacteria that can cause two major diseases-periodontitis and caries. The relationship between periodontopathic bacteria and systemic diseases has been explored for several years. The concept of the oral cavity as a source of distant infection has been debated for at least a century. This review will discuss the historic aspects of the development of the focal infection theory, the reasons for its demise, its re-emergence and current status. (C) 2013 Elsevier Ltd. All rights reserved.
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