4.1 Article

Quantitative analysis of initial adhesion of bacterial vaginosis-associated anaerobes to ME-180 cells

Journal

ANAEROBE
Volume 23, Issue -, Pages 1-4

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.anaerobe.2013.07.007

Keywords

Lactobacilli; Gardnerella vaginalis; Bacterial vaginosis; ME-180; Vaginal epithelial cells

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Funding

  1. European Union funds (FEDER/COMPETE)
  2. national funds (FCT) [FCOMP-01-0124-FEDER-008991 (PTDC/BIA-MIC/098228/2008)]
  3. Fundação para a Ciência e a Tecnologia [PTDC/BIA-MIC/098228/2008] Funding Source: FCT

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Bacterial vaginosis is the leading vaginal disorder but the transition from health to this dysbiotic condition remains poorly characterized. Our goal was to quantify the ability of BV-associated anaerobes to adhere to epithelial cells in the presence of lactobacilli. Gardnerella vaginalis outcompeted Lactobacillus crispatus and Lactobacillus iners actually enhanced its adherence. (c) 2013 Elsevier Ltd. All rights reserved.

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