Journal
JOURNAL OF NEUROSCIENCE METHODS
Volume 166, Issue 1, Pages 99-103Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jneumeth.2007.06.032
Keywords
object recognition; adolescence; activity chambers
Categories
Funding
- NIDA NIH HHS [R01 DA013137, K02 DA014401, R01 DA013712, R01 DA013965, R01 DA009160] Funding Source: Medline
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The novel object recognition task is gaining popularity for its ability to test a complex behavior which relies on the integrity of memory and attention systems without placing undue stress upon the animal. While the task places few requirements upon the animal, it traditionally requires the experimenter to observe the test phase directly and record behavior. This approach can severely limit the number of subjects which can be tested in a reasonable period of time, as training and testing occur on the same day and span several hours. The current study was designed to test the feasibility of automation of this task for adolescent rats using standard activity chambers, with the goals of increased objectivity, flexibility, and throughput of subjects. (C) 2007 Elsevier B.V. All rights reserved.
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