4.5 Article

N-heterocyclic carbene catalyzed reaction of enals and diaryl-1,2 diones via homoenolate:: Synthesis of 4,5,5-trisubstituted γ-butyrolactones

Journal

SYNTHESIS-STUTTGART
Volume -, Issue 20, Pages 3195-3200

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-990781

Keywords

lactones; homoenolate; N-heterocyclic carbene; benzil; thenil; furil

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Nucleophilic heterocyclic carbene (NHC)-catalyzed annulation of enals proceeds with variety of 1,2-dicarbonyl compounds, leading to the formation of 4,4,5-trisubstituted gamma-butyrolactones.

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