4.5 Article

Highly efficient and clean method for direct α-iodination of aromatic ketones

Journal

SYNTHESIS-STUTTGART
Volume -, Issue 20, Pages 3113-3116

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-983880

Keywords

aromatic ketones; iodine; alpha-iodo ketones; multifunctional; reagent; self-sorting

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Under neutral reaction conditions, aromatic ketones were transformed into the corresponding a.-iodo ketones in high yields by the combination of copper(II) oxide and iodine. The reaction mechanism showed that copper(II) oxide played multiple roles through random self-sorting.

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