Journal
SCIENCE
Volume 318, Issue 5849, Pages 426-430Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1147241
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Funding
- NHLBI NIH HHS [HL 74151, R01 HL074151-04, R01 HL074151] Funding Source: Medline
- NIDCR NIH HHS [R37 DE014193, R01 DE014193, R01 DE014193-03, DE 14193] Funding Source: Medline
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We report a method to form multifunctional polymer coatings through simple dip-coating of objects in an aqueous solution of dopamine. Inspired by the composition of adhesive proteins in mussels, we used dopamine self-polymerization to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics. Secondary reactions can be used to create a variety of ad-layers, including self-assembled monolayers through deposition of long-chain molecular building blocks, metal films by electroless metallization, and bioinert and bioactive surfaces via grafting of macromolecules.
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