Journal
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
Volume 119, Issue 1-2, Pages 33-37Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijfoodmicro.2007.07.022
Keywords
mycotoxins; multi-toxin analysis; conjugated mycotoxins; mass spectrometry; LC-MS/MS
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About 300-400 mycotoxins are known today. To some extent these compounds show very different physicochemical properties, which led to a vast quantity of analytical methods for single toxins or certain classes of mycotoxins in a variety of matrices. Due to synergistic effects of co-occuring toxins, endeavors have been made to simultaneously detect and quantify several classes of mycotoxins. This paper discusses several of the published LC-MS/MS multi-mycotoxin-methods and also introduces a new method, which allows the concurrent detection and quantification of 90 major mycotoxins and other secondary fungal metabolites in cereals. Even more, known plant derived metabolites of mycotoxins, like zearalenone-4-glucoside or deoxynivalenol-3-glucoside are included in this method. The significance of mycotoxin conjugates is briefly discussed as well. (C) 2007 Elsevier B.V. All rights reserved.
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