Journal
ORGANIC LETTERS
Volume 9, Issue 22, Pages 4503-4506Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol701826x
Keywords
-
Categories
Ask authors/readers for more resources
[GRAPHICS] Melting temperatures of DNA duplexes containing the phenoxazine (P) and G-clamp (X) cytosine analogues exhibited a strong and unusual dependence on the nucleoside flanking the modified nucleobase, and the same trend was observed in PNA-DNA duplexes incorporating X in the PNA chain. Molecular dynamics simulations of the DNA duplexes show that generalized stacking (including secondary interactions of the ammonium group of X) and hydrogen bonding are good descriptors of the different duplex stabilities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available