Journal
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
Volume 1, Issue 6, Pages 465-468Publisher
WILEY
DOI: 10.1002/term.55
Keywords
stem cell transplantation; biomatrices; Matrigel; Collagen I; Puramatrix; tissue engineering; molecular imaging
Categories
Funding
- NHLBI NIH HHS [K08 HL074883, R21 HL089027, HL074883, HL089027] Funding Source: Medline
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Therapeutic effects from injection of stem cells are often hampered by acute donor cell death as well as migration away from damaged areas. This is likely, due to the fact that injected cells do not have the physical and biochemical cues for ordered engrafment. Here we evaluate 3 common biomatrices (Matrigel, Collagen I, Purmatrix) that has the potential of providing suitable scaffolds needed to enhance stem cell survival. The longitudinal fate of transplanted stem cells was monitored by reporter imaging techniques. Copyright (c) 2007 John Wiley & Sons, Ltd.
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