Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 35, Issue -, Pages 1321-1324Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST0351321
Keywords
directly observed therapy short course (DOTS); moxifloxacin; PA-824; R207910; serine/threonine kinase; SQ109
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The need for better drugs to treat tuberculosis has never been greater. Despite insufficient funding for discovery research, intensive efforts have been made to find and develop new lead compounds capable of reducing the duration of the present treatment known as DOTS (directly observed therapy short course), from 6 to under 4 months. This minireview describes the progress achieved during the last 5 years and highlights some of the successes without neglecting the problems.
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