Journal
JOURNAL OF BACTERIOLOGY
Volume 189, Issue 22, Pages 8387-8391Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00736-07
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Funding
- NIGMS NIH HHS [GM066786, R01 GM066786] Funding Source: Medline
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The Vibrio fischeri quorum-sensing signal N-3-oxohexanoyl-L-homoserine lactone (30C6-HSL) activates expression of the seven-gene luminescence operon. We used microarrays to unveil 18 additional 30C6-HSL-controlled genes, 3 of which had been identified by other means previously. We show most of these genes are regulated by the 30C6-HSL-responsive transcriptional regulator LuxR directly. This demonstrates that V. fischeri quorum sensing regulates a substantial number of genes other than those involved in light production.
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