Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 17, Issue 21, Pages 5868-5871Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.08.012
Keywords
abietane-type diterpene; taxodistine A; taxodistine B; tubulin
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Two new abietane-type diterpenes, taxodistines A (1) and 13 (2), have been isolated by the guidance of inhibitory effect of tubulin polymerization from the fruits of Taxodium distichum and the structures were elucidated by using 2D NMR data. Taxodistine B (2) showed inhibition of tubulin polymerization. (c) 2007 Elsevier Ltd. All rights reserved.
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