Journal
CHINESE JOURNAL OF CHEMISTRY
Volume 25, Issue 11, Pages 1686-1689Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.200790311
Keywords
Knoevenagel condensation; coumarin; salicylaldehyde; L-proline; beta-ketoester; solvent-free synthesis
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L-Proline was utilized as an efficient organo-catalyst for the environmentally benign synthesis of 3-substituted. coumarins by the Knoevenagel condensation of substituted 2-hydroxybenzaldehydes with reactive methylene compounds under solvent free conditions.
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