4.4 Article

Substrate and product analogues as human O-GlcNAc transferase inhibitors

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

John A. Hanover et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)

Article Biochemistry & Molecular Biology

In Vivo Imaging of Caenorhabditis elegans Glycans

Scott T. Laughlin et al.

ACS CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

GIcNAcstatins are nanomolar inhibitors of human O-GIcNAcase inducing cellular hyper-O-GIcNAcylation

Helge C. Dorfmueller et al.

BIOCHEMICAL JOURNAL (2009)

Article Biochemistry & Molecular Biology

Portrait of an Enzyme, a Complete Structural Analysis of a Multimodular β-N-Acetylglucosaminidase from Clostridium perfringens

Elizabeth Ficko-Blean et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Endocrinology & Metabolism

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity

Ronald J. Copeland et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

Molecular mechanisms of O-GlcNAcylation

Ramon Hurtado-Guerrero et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Structural insights into mechanism and specificity of O-GlcNAc transferase

Andrew J. Clarke et al.

EMBO JOURNAL (2008)

Article Biochemistry & Molecular Biology

Antisense glutaminase inhibition modifies the O-GlcNAc pattern and flux through the hexosamine pathway in breast cancer cells

Ana C. Donadio et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

Scott A. Yuzwa et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation

Carlos Martinez-Fleites et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Modification of topoisomerase I activity by glucose and by O-GlcNAcylation of the enzyme protein

Noa Noach et al.

GLYCOBIOLOGY (2007)

Review Multidisciplinary Sciences

Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins

Gerald W. Hart et al.

NATURE (2007)

Review Biochemistry & Molecular Biology

O-GlcNAc modification in diabetes and Alzheimer's disease

Wagner B. Dias et al.

MOLECULAR BIOSYSTEMS (2007)

Article Chemistry, Multidisciplinary

GlcNAcstatin:: A picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-GlcNAcylation levels

Helge C. Dorfmueller et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Biochemistry & Molecular Biology

Synthesis of the C1-phosphonate analog of UDP-GlcNAc

Robert Chang et al.

CARBOHYDRATE RESEARCH (2006)

Article Multidisciplinary Sciences

Caenorhabditis elegans ortholog of a diabetes susceptibility locus:: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer

Michele E. Forsythe et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis

FV Rao et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity

RJ Dennis et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Cardiac & Cardiovascular Systems

Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia

J Liu et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)

Article Chemistry, Organic

A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase

KA Stubbs et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2006)

Article Chemistry, Multidisciplinary

Discovery of O-GlcNAc transferase inhibitors

BJ Gross et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Biochemistry & Molecular Biology

O-GlcNAcase uses substrate-assisted catalysis -: Kinetic analysis and development of highly selective mechanism-inspired inhibitors

MS Macauley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Cardiovascular effects of endomorphins in alloxan-induced diabetic rats

J Liu et al.

PEPTIDES (2005)

Article Biochemistry & Molecular Biology

Molecular modeling insights into the catalytic mechanism of the retaining galactosyltransferase LgtC

I Tvaroska

CARBOHYDRATE RESEARCH (2004)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Review Chemistry, Multidisciplinary

Total synthesis and biological evaluation of the protein phosphatase 2A inhibitor cytostatin and analogues

L Bialy et al.

CHEMISTRY-A EUROPEAN JOURNAL (2004)

Software Review Chemistry, Multidisciplinary

HKL2MAP:: a graphical user interface for macromolecular phasing with SHELX programs

T Pape et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2004)

Article Cell Biology

O-GlcNAc modification:: a nutritional sensor that modulates proteasome function

NE Zachara et al.

TRENDS IN CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

An evolving hierarchical family classification for glycosyltransferases

PM Coutinho et al.

JOURNAL OF MOLECULAR BIOLOGY (2003)

Article Cell Biology

Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion

K Liu et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)

Article Multidisciplinary Sciences

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

DA McClain et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase

RJ Konrad et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Chemistry, Organic

Improved chemical synthesis of UDP-galactofuranose

AL Marlow et al.

ORGANIC LETTERS (2001)

Article Chemistry, Organic

α-GlcNAc thioconjugates

S Knapp et al.

JOURNAL OF ORGANIC CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a β-N-acetylglucosaminidase

N Comtesse et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Article Chemistry, Organic

Synthesis and characterization of an anomeric sulfur analogue of CMP-sialic acid

SB Cohen et al.

JOURNAL OF ORGANIC CHEMISTRY (2000)

Article Multidisciplinary Sciences

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

R Shafi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Multidisciplinary Sciences

Glucose stimulates protein modification by O-linked GlcNAc in pancreatic β cells:: Linkage of O-linked GlcNAc to β cell death

K Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)