Journal
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
Volume 29, Issue 11, Pages 906-908Publisher
ELSEVIER INC
DOI: 10.1016/S1701-2163(16)32656-1
Keywords
Statin; pregnancy; teratogen
Categories
Funding
- Canadian Institute for Health Research
- Clinician Scientist Training Program
- Ontario Student Opportunity Trust Fund-Hospital for Sick Children Foundation Student Scholarship Program
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Although statins have been identified as potential teratogens on the basis of theoretical considerations and small case series, the available evidence is far from conclusive. In fact, epidemiological data collected to date suggest that statins are not major teratogens. The actual risk for an exposed pregnancy seems to be small, if present at all, and does not by itself warrant termination of pregnancy. Nevertheless, given the scarcity of available data, it is still advisable to avoid use of these drugs in patients who are planning pregnancy in order to reduce the risks as much as possible.
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