Journal
JOURNAL OF INORGANIC BIOCHEMISTRY
Volume 101, Issue 11-12, Pages 1692-1698Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jinorgbio.2007.07.007
Keywords
amphiphilic siderophore; marine bacteria; marinobactins; iron; lipidic peptide
Funding
- NIGMS NIH HHS [R01 GM038130-14, R01 GM038130-16, R01 GM038130, GM38130, R01 GM038130-15] Funding Source: Medline
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Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the amphiphilic siderophores partition indiscriminately in microbial and other membranes. An alternative method to distinguish amphiphilic siderophore partitioning versus siderophore-mediated active uptake for Fe(III)-marinobactin E has been developed. In addition, a new member of the marinobactin family of siderophores is also reported, marinobactin F, which has a C-18 fatty acid with one double bond and which is substantially more hydrophobic that marinobactins A-E. (C) 2007 Elsevier Inc. All rights reserved.
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