Journal
ELECTROCHEMISTRY COMMUNICATIONS
Volume 9, Issue 11, Pages 2734-2738Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2007.09.009
Keywords
Fe3O4@SiO2 nanoparticles; ferrocene monocarboxylic acid; glucose oxidase; Biosensors; chitosan
Categories
Ask authors/readers for more resources
A novel amperometric glucose biosensor was developed by entrapping glucose oxidase (GOD) in chitosan (CS) composite doped with ferrocene monocarboxylic acid-modified magnetic core-shell Fe3O4@SiO2 nanoparticles (FMC-AFSNPs). It is shown that the obtained magnetic bio-nanoparticles attached to the surface of a carbon paste electrode (CPE) with the employment of a permanent magnet showed excellent electrochemical characteristics and at the same time acted as mediator to transfer electrons between the enzyme and the electrode. Under optimal conditions, this biosensor was able to detect glucose in the linear range from 1.0 x 10(-5) to 4.0 x 10(-3) M with a detection limit of 3.2 mu M (S/N = 3). This immobilization approach effectively improved the stability of the electron transfer mediator and is promising for construction of biosensor and bioelectronic devices. (C) 2007 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available