Journal
NATURE CHEMICAL BIOLOGY
Volume 3, Issue 11, Pages 709-710Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nchembio.2007.39
Keywords
-
Categories
Ask authors/readers for more resources
Modifications of the canonical structures of DNA and RNA play critical roles in cell physiology, DNA replication, transcription and translation in all organisms. We now report that bacterial dnd gene clusters incorporate sulfur into the DNA backbone as a sequence-selective, stereospecific phosphorothioate modification. To our knowledge, unlike any other DNA or RNA modification systems, DNA phosphorothioation by dnd gene clusters is the first physiological modification described on the DNA backbone.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available