4.6 Article

Socioeconomic status at birth is associated with risk of schizophrenia: Population-based multilevel study

Journal

SCHIZOPHRENIA BULLETIN
Volume 33, Issue 6, Pages 1373-1378

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/schbul/sbm032

Keywords

social causation theory; social selection theory; parental education; parental occupation; residential area; multilevel analyses

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Funding

  1. NIMH NIH HHS [2 K24 MH001699, R01 MH059114, R01 MH059114-01A1, K24 MH001699, K24 MH001699-01A2] Funding Source: Medline

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Background: Inconsistent findings obscure understanding the relationship between socioeconomic status (SES) and schizophrenia. The aim of the current study was to test the association between individual and community SES at birth and risk of schizophrenia. Method: Population based longitudinal follow forward study of a 13-year birth cohort (n 5 71 165). Effects of individual and community socioeconomic variables were examined using multilevel regression in MLwiN. Results: Years of education of fathers and mothers, respectively, (0-8 vs 131 odds ratio [ OR] 5 1.17, P <.0001; OR 5 1.14, P <.001) lower occupational status of fathers (OR = 1.29, P = .036), and poorer residential area SES (OR = 1.26, P = .012) were risk factors for schizophrenia. Conclusions: Individual- and community-level SES at the time of birth are associated with an increased risk of schizophrenia.

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