Journal
JOURNAL OF BIOMEDICAL OPTICS
Volume 12, Issue 6, Pages -Publisher
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.2823076
Keywords
virtual point detector; ring detector; photoacoustic imaging; small animal imaging; aperture effect; resolution; signal-to-noise ratio
Funding
- NIBIB NIH HHS [R01 EB000712] Funding Source: Medline
- NINDS NIH HHS [R01 NS046214, R01 NS46214] Funding Source: Medline
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We image a rat cerebral cortex in situ by using a ring-based ultrasonic virtual point detector developed previously. Compared to the image generated by a finite-aperture detector, the image generated by the virtual point detector has a uniformly distributed resolution throughout the imaged area, owing to the lack of aperture effect of the ultrasonic detector. At the periphery of the image, the signal-to-noise ratio of the image obtained by the virtual point detector is also better than that of a finite-aperture detector. Furthermore, the virtual point detector can be scanned inside the brain to improve the local signal-to-noise ratio. (C) 2007 Society of Photo-Optical Instrumentation Engineers.
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