Journal
TETRAHEDRON
Volume 63, Issue 46, Pages 11444-11450Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2007.08.050
Keywords
3-spiro-2-oxindoles; pyrano[2,3-c]pyrazol; methylene active nitriles; Michael reaction; X-ray diffraction analysis
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4,3'-Spiro[(6-amino-5-R-3-methyl-2H,4H-pyrano[2,3-c]pyrazolo)-2'-oxindoles] were synthesized based on the three-component condensation of isatins with 3-methyl-pyrazolone-5 and respective methylene active nitriles in the presence of basic catalysts. The molecular structure of the resulting compounds was proved unambiguously by X-ray diffraction. (C) 2007 Elsevier Ltd. All rights reserved.
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