Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 17, Issue 22, Pages 6230-6233Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.09.027
Keywords
Gd-complex; Eu-complex; MRI; optical imaging
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Gd and Eu complexes of PMN-tetraacetic acid show interesting properties either for MRI or for optical imaging; that is, for the Gd-complex, a high proton relaxivity with favorable water residence time; for the Eu-complex, a luminescence lifetime of 400 mu s at room temperature compatible with the use of time-resolved luminescence technique. Both complexes have a good stability in physiological medium. (C) 2007 Elsevier Ltd. All rights reserved.
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