One-pot synthesis of well-defined amphiphilic and adaptative block copolymers via versatile combination of Click chemistry and ATRP

Well-defined amphiphilic PCL-b-PDMAEMA block copolymers were successfully synthesized by a combination of ATRP and click chemistry following either a commutative two-step procedure or a straightforward one-pot process using CuBr center dot 3Bpy as the sole catalyst. Compared to the traditional coupling method, combining ATRP and click chemistry even in a one-pot process allows the preparation of PCL-b-PDMAEMA diblock copolymers characterized by