4.8 Article

Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones

Journal

ORGANIC LETTERS
Volume 9, Issue 24, Pages 4959-4962

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AMER CHEMICAL SOC
DOI: 10.1021/ol7020669

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One-pot combination of silver triflate and proline catalysis is highly effective for the synthesis of 1,2-dihydroisoquinoline derivatives via multicomponent reactions of 2-alkynylbenzaidehydes, amines, and ketones.

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