Journal
CHEMBIOCHEM
Volume 8, Issue 17, Pages 2035-2038Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbic.200700354
Keywords
cage compounds; gamma-aminobutyric acid; GABA; photolysis; ruthenium
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An inorganic-based caged compound of the inhibitory neurotransmitter, gamma-amino butyric acid (GABA), was prepared and photolysed by light at 450 nm with the highest uncaging quantum yield reported to date. GABA ion channels were activated by irradiation in a biological preparation by using this caged compound.
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