Journal
VACCINE
Volume 25, Issue 48, Pages 8172-8179Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2007.09.031
Keywords
pertussis; vaccine; serology
Categories
Ask authors/readers for more resources
Persistence of antibodies following a single dose of Tdap, vaccine (tetanus, diphtheria, and five-component acellular pertussis vaccine for use in individuals past childhood) was evaluated in a follow-up of adolescents (N = 324) and adults (N = 644) who had received Tdap in earlier clinical trials. Outcome measures were seroprotection (tetanus and diphtheria) or seropositivity (pertussis) and geometric mean titers. Humoral immune responses to all antigens were robust 1 month after initial immunization; antibodies exceeded pre-immunization levels 1, 3, and 5 years later. These data will contribute to selecting the optimal interval for booster doses of Tdap. Crown Copyright (c) 2007 Published by Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available