Journal
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Volume 18, Issue 12, Pages 3199-3205Publisher
AMER SOC NEPHROLOGY
DOI: 10.1681/ASN.2007040440
Keywords
-
Categories
Funding
- NIDDK NIH HHS [T32 DK007785, T32-DK-07785] Funding Source: Medline
Ask authors/readers for more resources
Case reports and case series suggest a potential link between oral sodium phosphosocla used in preparation for outpatient colonoscopy and kidney injury, but controlled studies are lacking. We performed a case-control study nested within a cohort of patients with baseline serum creatinine <= 1.5 mg/dL who underwent outpatient colonoscopy. We defined a case of kidney injury as a rise in serum creatinine >= 0.5 mg/dL and/or 25% between values obtained during the 6 months prior and during the 6 months following colonoscopy (n = 116). We found that exposure to phosphosocla was not more common among patients with incident kidney injury (adjusted odds ratio 0.70; 95% Cl 0.44-1.11), and sensitivity analyses that considered other definitions of kidney injury did not suggest a different conclusion. Therefore, despite a plausible link, the current data do not support an association between oral phosphosocla and kidney injury at 6 months follow-up among patients with baseline serum creatinine <= 1.5 mg/dL. Further studies are warranted to validate and generalize our findings.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available