Journal
MICROBIAL DRUG RESISTANCE
Volume 13, Issue 4, Pages 235-239Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/mdr.2007.767
Keywords
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Funding
- NIGMS NIH HHS [GM008722-07] Funding Source: Medline
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Klebsiella pneumoniae isolates harboring KPC enzymes have been identified in many geographical areas since 2001. Numerous problems exist in the detection and treatment of patients with such isolates. The clinical characteristics and molecular epidemiology associated with 12 randomly chosen patients in whom these enzymes were detected by molecular methods are described. This is the first description of the identification of carbapenem-resistant K. pneumoniae isolates harboring KPC beta-lactamases at the Veterans Administration Hospital in New Jersey (VA NJHCS). Because recognition of carbapenem resistance in K. pneumoniae due to KPC enzymes can only be achieved by molecular methods, detection in the Clinical Microbiology Laboratory by routine methods will continue to be difficult, leading to dilemmas in treatment.
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