Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 51, Issue 12, Pages 4518-4520Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00808-07
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- NIAID NIH HHS [R21 AI054858] Funding Source: Medline
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Ureteral stents coated with the quorum-sensing inhibitor RNAIII-inhibiting peptide (RIP) were implanted in rat bladders and shown to suppress Staphylococcus aureus formation on the stent and in urine and was especially effective when combined with teicoplanin. Coating ureteral stents with RIP thus increases the efficacy of teicoplanin in preventing ureteral stent-associated staphylococcal infections.
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