Journal
TRANSPLANTATION PROCEEDINGS
Volume 39, Issue 10, Pages 3500-3501Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.transproceed.2007.09.040
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We report a 62-year-old female liver transplant patient who presented with sirolimus (SIR)-related pneumonitis (SIP) treated with a switch to everolimus (EVER). At 13-month follow-up, the patient is on EVER monotherapy with no recurrence of SIP. Despite common mechanisms of action, the safety profile of EVER is different from SIR, and a switch from SIR to EVER should be contemplated in cases of SIP to allow patients to benefit from the antifibrotic properties of antiproliferative immunosuppressants.
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