Journal
INDIAN JOURNAL OF PHARMACOLOGY
Volume 39, Issue 6, Pages 281-283Publisher
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/0253-7613.39147
Keywords
antioxidant activity; gossypin; nevadensin
Categories
Ask authors/readers for more resources
Objectives: The antioxidant potential of gossypin and nevadensin, two flavonoid compounds, were evaluated by in vitro methods. Materials and Methods: Gossypin, nevadensin, and the reference standard, butylated hydroxyl toluene (BHT), were evaluated for DPPH (1,1-diphenyl-2-picrylhydrazyl), nitric oxide, superoxide, and hydroxyl radical scavenging activity. Results: Gossypin and BHT showed the potential for significant DPPH radical inhibition of up to 88.52 and 91.45% at 100 mu g/ml concentration. With a 100 mu g/ml concentration of gossypin, the in vitro nitric oxide, superoxide, and hydroxyl radical scavenging activity was found to be 74.00, 74.22, and 67.15%, respectively; and with 100 mu g/ml of BHT the corresponding values were 82.24, 81.76, and 73.03% of inhibition, respectively. Conclusion: The study results showed that gossypin has significant antioxidant activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available