Journal
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
Volume 5, Issue 6, Pages 1019-1030Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/14787210.5.6.1019
Keywords
cryptococcosis; HIV; infection; treatment
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The HIV pandemic has been associated with a rise in the prevalence of primary and recurrent cryptococcosis. Evidence-based treatment algorithms exist for the use of antifungal drugs and maintaining normal intracranial pressure in HIV-infected hosts with cryptococcal meningitis. Further investigation is needed for the treatment of cases with refractory infections and cryptococcosis-related immune reconstitution syndrome, along with the optimal use of adjuvant therapies. Primary and secondary prevention strategies remain at the crux of global control strategies for cryptococcal disease.
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