4.7 Article

Cavitary disease and quantitative sputum bacillary load in cases of pulmonary tuberculosis

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 45, Issue 12, Pages 4064-4066

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01780-07

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Funding

  1. NIAID NIH HHS [N01AI95383] Funding Source: Medline

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We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease.

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