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Active and passive immunity, vaccine types, excipients and licensing

Journal

OCCUPATIONAL MEDICINE-OXFORD
Volume 57, Issue 8, Pages 552-556

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/occmed/kqm110

Keywords

active immunity; immunization; immunoglobulin preparations; passive immunity; vaccine excipients; vaccine licensing; vaccine types

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Immunity is the state of protection against infectious disease conferred either through an immune response generated by immunization or previous infection or by other non-immunological factors. This article reviews active and passive immunity and the differences between them: it also describes the four different commercially available vaccine types (live attenuated, killed/inactivated, subunit and toxoid): it also looks at how these different vaccines generate an adaptive immune response.

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