Journal
AMERICAN JOURNAL OF TRANSPLANTATION
Volume 9, Issue 10, Pages 2262-2269Publisher
WILEY
DOI: 10.1111/j.1600-6143.2009.02775.x
Keywords
Graft dysfunction; lung preservation; lung transplantation; machine perfusion; machine preservation
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Funding
- Canadian Institute of Health Research [MOP-64370, MOP-13270, MOP-42546]
- NIH [DK54759]
- Astellas Pharma Inc.
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [P30DK054759] Funding Source: NIH RePORTER
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Treatment of injured donor lungs ex vivo to accelerate organ recovery and ameliorate reperfusion injury could have a major impact in lung transplantation. We have recently demonstrated a feasible technique for prolonged (12 h) normothermic ex vivo lung perfusion (EVLP). This study was performed to examine the impact of prolonged EVLP on ischemic injury. Pig donor lungs were cold preserved in Perfadex
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