4.6 Article

CCR5 Is Required for Regulation of Alloreactive T-Cell Responses to Single Class II MHC-Mismatched Murine Cardiac Grafts

Journal

AMERICAN JOURNAL OF TRANSPLANTATION
Volume 9, Issue 10, Pages 2251-2261

Publisher

WILEY
DOI: 10.1111/j.1600-6143.2009.02786.x

Keywords

Chemokine receptors; CD4 T cells; transplantation immunology

Funding

  1. NIH [RO1 A140459, A174740, F30 HL094005, T32 GM07250]
  2. Case Medical Scientist Training Program

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The effector CD4 T-cell response in wild-type C57BL/6 recipients of single class II MHC-disparate B6.H-2 100 days), the allografts were acutely rejected within 25 days in CCR5

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