Journal
AMERICAN JOURNAL OF THERAPEUTICS
Volume 19, Issue 4, Pages E136-E138Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MJT.0b013e3181ed838c
Keywords
hydralazine vasculitis; hydralazine pulmonary-renal syndrome; drug-induced vasculitis; hydralazine pulmonary hemorrhage; hydralazine glomerulonephritis
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Drug-induced lupus erythematosus differs in its manifestation from drug-induced vasculitis. The former is associated with characteristic symptoms that improve following discontinuation, whereas the latter is predominantly an antineutrophil cytoplasmic antibody (ANCA) positive small vessel vasculitis involving the kidneys, skin, and lungs. We present a case of advanced disease in an elderly Caucasian woman requiring corticosteroids, and immunosuppressive therapy, who was on hydralazine for >2 years.
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