Journal
AMERICAN JOURNAL OF THERAPEUTICS
Volume 16, Issue 2, Pages 193-196Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MJT.0b013e3180a5bd83
Keywords
bupropion; overdose; QRS prolongation; sodium bicarbonate
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We describe a case of bupropion-associated QRS prolongation that was unresponsive to intravenous bolus therapy of sodium bicarbonate. Bupropion may cause seizures and conduction delays similar to tricyclic antidepressants in the overdose setting by an unknown mechanism.
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