4.2 Article

Synthesis and cytotoxicity of analogues of the marine secondary metabolite, 2-deoxylapachol

Journal

JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 12, Pages 677-679

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.3184/030823407X270437

Keywords

2-deoxylapachol; 1,4-naphthoquinones; oesophageal cancer

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The syntheses of four 2-substituted 1,4 naphthoquinones, related to the marine natural product 2-deoxylapachol, are reported. All four synthetic compounds were cytotoxic to WHCO1 oesophageal cancer cells.

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